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KMID : 0043320060290090786
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Archives of Pharmacal Research
2006 Volume.29 No. 9 p.786 ~ p.794
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Glucose-lowering Effect of Powder Formulation of African Black Tea Extract in KK-Ay/TaJcl Diabetic Mouse
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Shoji Yoko
Nakashima Hideki
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Abstract
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We observed the suppressive effect of a powder formulation of African black tea extract prepared from the leaves of Camellia sinensis on type 2 non-insulin dependent diabetic mice, KKA y/TaJcl. Black tea extract significantly showed suppressive effect of the elevation of blood glucose on oral glucose tolerance test of 8 week-old KK-Ay/TaJcl mice (P<0.05). Long-term treatment with black tea extract showed significant suppression of post-prandial blood glucose and obesity (P<0.05). The weight of the intestine of mice treated with black tea extract was significantly reduced (P<0.05). From these results, African black tea used in this study showed a suppressive effect on the elevation of blood glucose during food intake and the body weight.
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KEYWORD
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Black tea extract, Glucose-lowering, Theaflavin, Tea polyphenol, Adipocyte
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